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ArticleOpen Access30 Oct 2024 Polyclonality overcomes Health obstacles in Apc-driven tumorigenesis Multicolour lineage tracing and mutagenesis reports in a mouse model exhibit that many intestinal tumours are polyclonal, with several clones exhibiting impartial Apc mutations driven by variances in KRAS and MYC signalling.Article30 Oct 2024 Myocar